Cancer Genomics
- Bruce Edgar
- From Fruit Fly Research To Precision Medicine
The precise control of cell proliferation is absolutely essential, not only for the development of growing plants and animals, but for the process of tissue homeostasis in adult living organisms. Loss of control over this process is a potential cause of cancer.
The research carried out in the Bruce Edgar Laboratory focuses on the mechanisms which control cell cycles and cell growth. Researchers apply a series of molecular, genetic and cell biology methods in order to discover and define genes and regulatory pathways which regulate the growth and proliferation of cells in vivo in different organs in the Drosophila model system.
Current projects are concerned with the control of the cell cycle exit at differentiation, the mechanism of growth-related endocycles, the regulation of nutrition-related cell growth using TOR signalling and the control of homeostatic growth in intestinal stem cells.
Language: English
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